Stomach ulcers, also known as gastric ulcers, are painful lesions on the lining of the stomach. Peptic ulcer disease includes stomach ulcers. Any ulcer that affects both the stomach and the small intestine is known as a peptic ulcer.When the thick coating of mucus that shields your stomach from digestive fluids is weakened, stomach ulcers develop. This permits the digestive acids to eat away at the stomach’s lining tissues, resulting in an ulcer.Although stomach ulcers are relatively treatable, they can develop serious if not treated properly.
An infection with the bacteria Helicobacter pylori (H. pylori) or long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs), such as aspirin, ibuprofen, or naproxen, nearly invariably causes stomach ulcers. Zollinger-Ellison syndrome is a rare illness that causes stomach and intestine ulcers by boosting the body’s acid production. This condition is thought to be responsible for fewer than 1% of all peptic ulcers.Peptic ulcers are caused by the Helicobacter pylori bacteria (H. pylori). Many areas of gastroenterology, particularly the management of stomach ulcers, were revolutionised when this microbe was discovered in 1983.In Australia, it is estimated that one in every three adults over the age of 40 is infected with this type of bacteria. The microorganisms that dwell in the stomach lining create compounds that cause discomfort and inflammation. H. pylori is the direct cause of one-third of stomach ulcers and a contributing factor in the remaining three-fifths. Inflammation of the stomach (gastritis) and dyspepsia are two more problems induced by this virus (indigestion).
The bacterium may possibly have a role in the development of stomach malignancies, according to researchers. The illness is more frequent among the impoverished and those who are institutionalised. In underdeveloped populations, the route of transmission is uncertain, however it is assumed to involve sharing food or utensils, coming into touch with infectious vomit, and sharing water (such as well water). It’s crucial to understand how NSAIDs function in order to comprehend how they induce peptic ulcer disease. Nonsteroidal anti-inflammatory medicines (NSAIDs) are medications that are used to treat pain, fever, and inflammation (swelling).Two enzymes in your body create substances that induce pain, inflammation, and fever in your cells. NSAIDs act by preventing or lowering the production of these enzymes in the body. One of the enzymes, however, also creates a substance that shields the stomach lining from stomach acid and aids in bleeding management.NSAIDs raise your risk of developing a peptic ulcer by blocking or reducing the quantity of this enzyme in your body.
Bleeding from stomach ulcers is more prevalent in persons who use blood thinners such warfarin, aspirin, or clopidogrel (Plavix), and these patients should also take anti-ulcer medicine on a regular basis to avoid this problem.Untreated severe ulcers can burn through the stomach wall, enabling digestive fluids and food to flow into the abdominal cavity. A perforated ulcer is the medical term for this situation. In most cases, surgery is required right away.